Prerequisites and compatibility
The Yosshi's input and output can be created, processed and studied entirely on-line via the web-interface. The only software required on the user side is an HTML5-compatible web-browser. In addition, you may wish to download the output data to your computer and study them off-line. For this you may need the PyMol molecular graphics engine.
All steps of the Yosshi+Mustguseal web-server protocol are executed entirely on the server side. You do not need any specific software on your side. The Yosshi's output is primarily web-based and viewable on the site. The Analysis section of the Results page offers interactive content for analysis of the produced results. Interactivity is implemented in HTML5 and therefore neither plugins nor Java are required. The only prerequisite for viewing the Analysis section of the Results page is an HTML5-compatible web-browser. Current versions of all major browsers support HTML5 as the default standard. The recommended web-browser for using Yosshi is Google Chrome The Yosshi web-server was checked for compatibility with the following Operating Systems (OS) and web-browsers (see below). Table legend: "Submit" - can be used to submit a new task to Yosshi; "Results Download" - can be used to download the results for the off-line analysis using the download links at the Results page; "Results On-line" - can be used to view and operate the results using interactive HTML5-based tools at the Analysis page; "Delete" - can be used to delete user data from the server using the Delete button (see more about task retraction at this page).
| OS | Browser | Submit | Results | Delete | |
| Download | On-line | ||||
| openSuSE 15.0 | Google Chrome 69.0.3497.100 | Yes | Yes | Yes | Yes |
| Mozilla Firefox 60.1 | Yes | Yes | Yes | Yes | |
| KDE Konqueror 5.0.97 | No | - | - | - | |
| Opera 56.0.3051.52 | Yes | Yes | Yes | Yes | |
| openSuSE 13.1 | Google Chrome 46.0.2490.80 | Yes | Yes | Yes | Yes |
| Mozilla Firefox 42.0 | Yes | Yes | Yes | Yes | |
| KDE Konqueror 4.11.5 | Yes | Yes | No | Yes | |
| Opera 12.15 | Yes | Yes | Limited | Yes | |
| Windows 8.1 | Google Chrome 71.0.3578.98 | Yes | Yes | Yes | Yes |
| Mozilla Firefox 64.0 | Yes | Yes | Yes | Yes | |
| Opera 57.0.3098.106 | Yes | Yes | Yes | Yes | |
| Internet Explorer 11.0.9600 | No | - | - | - | |
| Windows 7 | Google Chrome 71.0.3578.98 | Yes | Yes | Yes | Yes |
| Google Chrome 69.0.3497.100 | Yes | Yes | Yes | Yes | |
| Mozilla Firefox 64.0 | Yes | Yes | Yes | Yes | |
| Opera 57.0.3098.106 | Yes | Yes | Yes | Yes | |
| Internet Explorer 11.0.9600 | No | - | - | - | |
| Windows XP SP3 | Google Chrome 49.0.2623.112 | Yes | Yes | Yes | Yes |
| Internet Explorer 8.0.6001 | No | - | - | - | |
| iOS 12.1.2 | Safary 6.051 | Yes | No | Yes | Yes |
| Google Chrome 71.0.3578.89 | Yes | No | Yes | Yes | |
The PyMol molecular graphics engine will be required to operate the Yosshi annotation file on a local computer. PyMol can be installed from a Linux repository (e.g., in openSuSE you should try the "zypper in pymol" command), compiled from sources (recommended for advanced users only) or purchased from the distributor Schrödinger LLC (external link). Alternatively, the results of the Yosshi can be operated on-line using the built-in interactive analysis tools. Interactivity is implemented in HTML5 and therefore no plugins nor Java are required.